2025
Mok KC, Hallberg ZF, Procknow RR, Taga ME. 2025. Laboratory evolution of E. coli with a natural vitamin B12 analog reveals roles for cobamide uptake and adenosylation in methionine synthase-dependent growth. Journal of Bacteriology. 207(2):e00284-24.
Mok KC, Sokolovskaya OM, Deutschbauer AM, Carlson HK, Taga ME. 2025. Microbes display broad diversity in cobamide preferences. MSystems. 10(4):e01407-24.
ZI Alvarez-Aponte, RR Procknow, ME Taga. 2025. The Corrinoid Model for Dissecting Microbial Community Interactions Across Scales. Annual Review of Microbiology 79.
2024
Hallberg ZF, Nicolas AM, Alvarez-Aponte ZI, Mok KC, Sieradzki ET, Pett-Ridge J, Banfield JF, Carlson HK, Firestone MK, Taga ME. Soil microbial community response to corrinoids is shaped by a natural reservoir of vitamin B12. The ISME Journal. 18(1):wrae094.
2023
Taga ME, Ludington WB. 2023. Nutrient encryption and the diversity of cobamides, siderophores, and glycans. Trends in microbiology 31(2):115-119.
Green MA, Alvarez-Aponte ZI, Trotter VV, Taga ME. 2023. Draft Genome Sequence of Pedococcus sp. Strain 5OH_020, Isolated from California Grassland Soil. Microbiology Resource Announcements. 12(6): e00025-23.
Nicolas AM, Sieradzki ET, Pett-Ridge J, Banfield JF, Taga ME, Firestone MK, J Blazewicz SJ. 2023. A subset of viruses thrives following microbial resuscitation during rewetting of a seasonally dry California grassland soil. Nature Communications. 14(1):5835.
Pherribo GJ, Taga ME. 2023. Bacteriophage-mediated lysis supports robust growth of amino acid auxotrophs. The ISME Journal. 17(10):1785-1788.
Aumiller K, Scheffler R, Stevens ET, Güvener ZT, Tung E, Grimaldo AB, Carlson HK, Deutschbauer AM, Taga ME, Marco ML, Ludington WB. 2023. A chemically-defined growth medium to support Lactobacillus-Acetobacter sp. community analysis. Plos one. 18(10):e0292585.
RR Procknow, KJ Kennedy, M Kluba, LJ Rodriguez, ME Taga. 2023. Genetic dissection of regulation by a repressing and novel activating corrinoid riboswitch enables engineering of synthetic riboswitches. Mbio. 14(5):e01588-23.
2022
Mok KC, Hallberg ZF, Taga ME. 2022. Purification and detection of vitamin B12 analogs. Methods in Enzymology. 668:61-85.
Hallberg ZF, Seth EC, Thevasundaram K, Taga ME. 2022. Comparative analysis of corrinoid profiles across host-associated and environmental samples. Biochemistry. 61(24):2791-2796.
Gude S, Pherribo GJ, Taga ME. 2022. A salvaging strategy enables stable metabolite provisioning among free-living bacteria. S Gude, GJ Pherribo, ME Taga. Msystems. 7(4):e00288-22.
Kennedy KJ, Widner FJ, Sokolovskaya OM, Innocent LV, Procknow RR, Mok KC, Taga ME. 2022. Cobalamin riboswitches are broadly sensitive to corrinoid cofactors to enable an efficient gene regulatory strategy. MBio. 13(5):e01121-22.
2021
Sokolovskaya OM, Plessl T, Bailey H, Mackinnon S, Baumgartner MR, Yue WW, Froese DS, Taga ME. 2021. Naturally occurring cobalamin (B12) analogs can function as cofactors for human methylmalonyl-CoA mutase. Biochimie. 183:35-43.
Nicolas AM, Jaffe AL, Nuccio EE, Taga ME, Firestone MK, Banfield JF. 2021. Soil Candidate Phyla Radiation Bacteria Encode Components of Aerobic Metabolism and Co-occur with Nanoarchaea in the Rare Biosphere of Rhizosphere Grassland Communities. mSystems. 6(4):e0120520.
2020
Kennedy KJ, Taga ME. 2020. Cobamides (Quick guide). Current Biology. 30(2):R55-R56.
Gude S, Pherribo GJ, Taga ME. 2020. Emergence of Metabolite Provisioning as a By-Product of Evolved Biological Functions. mSystems. 5(3)
Shelton AN, Lyu X, Taga ME. 2020. Flexible cobamide metabolism in Clostridioides (Clostridium) difficile 630 Δerm. Journal of bacteriology. 202(2):e00584-19.
Mok K.C., Nicolas A.M., Hallberg Z.F., Deutschbauer A, Carlson H.K., Taga M.E.. 2020. Identification of a Novel Cobamide Remodeling Enzyme in the Beneficial Human Gut Bacterium Akkermansia muciniphila. mBio. 11(6)
Gude S, Taga ME. 2020. Multi-faceted approaches to discovering and predicting microbial nutritional interactions. Current Opinion in Biotechnology. 62:58-64.
Sokolovskaya O.M., Shelton A.N., Taga M.E.. 2020. Sharing vitamins: Cobamides unveil microbial interactions. Science. 369(6499)
Hallberg ZF, Taga ME. 2020. Taking the “Me” out of meat: A new demethylation pathway dismantles a toxin’s precursor. The Journal of Biological Chemistry. 295:11982-11983.
Nicolas AM, Jaffe AL, Nuccio EE, Taga ME, Firestone MK, Banfield JF. 2020. Unexpected diversity of CPR bacteria and nanoarchaea in the rare biosphere of rhizosphere-associated grassland soil. bioRxiv.
2019
Sokolovskaya OM, Mok KC, Park JD, Tran JL, Quanstrom KA, Taga ME. 2019. Cofactor Selectivity in Methylmalonyl Coenzyme A Mutase, a Model Cobamide-Dependent Enzyme. mBio. 10(5):e01303-19.
Shelton AN, Seth EC, Mok KC, Han AW, Jackson SN, Haft DH, Taga ME. 2019. Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics. ISME Journal. 13:789-804.
2018
Hazra AB, Ballou DP, Taga ME. 2018. Unique biochemical and sequence features enable BluB to destroy flavin and distinguish BluB from the flavin monooxygenase superfamily. Biochemistry.
2017
Liu X, Turchi B, Mok KC, Taga ME, Miller MJ. 2017. HM2-phage resistant solventogenic Clostridium saccharoperbutylacetonicum N1-4 shows increased exopolysaccharide production. FEMS Microbiology Letters. 364(19):fnx191.
2016
Abreu NA, Taga ME. 2016. Decoding molecular interactions in microbial communities. FEMS Microbiology Reviews.
Crespo-Rivas JC, Guefrachi I, Mok KC, Villaécija‐Aguilar JA, Acosta‐Jurado S, Pierre O, Ruiz‐Sainz JE, Taga ME, Mergaert P, Vinardell JM. 2016. Sinorhizobium fredii HH103 bacteroids are not terminally differentiated and show altered O‐antigen in nodules of the Inverted Repeat‐Lacking Clade legume Glycyrrhiza uralensis. Environmental Microbiology. 8(18):2392-404.
2015
Mehta AP, Abdelwahed SH, Fenwick MK, Hazra AB, Taga ME, Zhang Y, Ealick SE, Begley TP. 2015. Anaerobic 5-Hydroxybenzimidazole Formation from Aminoimidazole Ribotide: An Unanticipated Intersection of Thiamin and Vitamin B₁₂ Biosynthesis. Journal of the American Chemical Society. 137(33):10444-7.
Hazra AB, Han AW, Mehta AP, Mok KC, Osadchiy V, Begley TP, Taga ME. 2015. Anaerobic biosynthesis of the lower ligand of vitamin B12. Proceedings of the National Academy of Sciences of the United States of America. 112(34):10792-7.
2014
Crofts TS, Men Y, Alvarez-Cohen L, Taga ME. 2014. A bioassay for the detection of benzimidazoles reveals their presence in a range of environmental samples. Frontiers in microbiology. 5:592.
Degnan PH, Barry NA, Mok KC, Taga ME, Goodman AL. 2014. Human gut microbes use multiple transporters to distinguish vitamin B₁₂ analogs and compete in the gut. Cell host & microbe. 15(1):47-57.
Men Y, Seth EC, Yi S, Crofts TS, Allen RH, Taga ME, Alvarez-Cohen L. 2014. Identification of specific corrinoids reveals corrinoid modification in dechlorinating microbial communities. Environmental microbiology.
Seth EC, Taga ME. 2014. Nutrient cross-feeding in the microbial world. Frontiers in microbiology. 5:350.
Crofts T S, Hazra AB, Tran JLA, Sokolovskaya OM, Osadchiy V, Ad O, Pelton JG, Bauer S, Taga ME. 2014. Regiospecific formation of cobamide isomers is directed by CobT. Biochemistry.
Men Y, Seth EC, Yi S, Allen RH, Taga ME, Alvarez-Cohen L. 2014. Sustainable growth of Dehalococcoides mccartyi 195 by corrinoid salvaging and remodeling in defined lactate-fermenting consortia. Applied and environmental microbiology. 80(7):2133-41.
Degnan PH, Taga ME, Goodman AL. 2014. Vitamin B12 as a Modulator of Gut Microbial Ecology. Cell Metabolism. 20(5):769–778.
2013
Hazra AB, Tran JLA, Crofts TS, Taga ME. 2013. Analysis of substrate specificity in CobT homologs reveals widespread preference for DMB, the lower axial ligand of vitamin B(12). Chemistry & biology. 20(10):1275-85.
Crofts TS, Seth EC, Hazra AB, Taga ME. 2013. Cobamide structure depends on both lower ligand availability and CobT substrate specificity. Chemistry & biology. 20(10):1265-74.
Mok KC, Taga ME. 2013. Growth inhibition of Sporomusa ovata by incorporation of benzimidazole bases into cobamides. Journal of bacteriology. 195(9):1902-11.
2012
Yu T-Y, Mok KC, Kennedy KJ, Valton J, Anderson KS, Walker GC, Taga ME. 2012. Active site residues critical for flavin binding and 5,6-dimethylbenzimidazole biosynthesis in the flavin destructase enzyme BluB. Protein science : a publication of the Protein Society. 21(6):839-49.
Yi S, Seth EC, Men Y-J, Stabler SP, Allen RH, Alvarez-Cohen L, Taga ME. 2012. Versatility in corrinoid salvaging and remodeling pathways supports corrinoid-dependent metabolism in Dehalococcoides mccartyi. Applied and environmental microbiology. 78(21):7745-52.
2011
Taga ME, Xavier KB. 2011. Methods for analysis of bacterial autoinducer-2 production. Current protocols in microbiology. Chapter 1:Unit1C.1.\
2010
Taga ME, Walker GC. 2010. Sinorhizobium meliloti requires a cobalamin-dependent ribonucleotide reductase for symbiosis with its plant host. Molecular plant-microbe interactions : MPMI. 23(12):1643-54.
2008
Taga ME, Walker GC. 2008. Pseudo-B12 joins the cofactor family. Journal of bacteriology. 190(4):1157-9.
Pereira CS, McAuley RJ, Taga ME, Xavier KB, Miller ST. 2008. Sinorhizobium meliloti, a bacterium lacking the autoinducer-2 (AI-2) synthase, responds to AI-2 supplied by other bacteria. Molecular microbiology. 70(5):1223-35.
2007
Taga ME. 2007. Bacterial signal destruction. ACS chemical biology. 2(2):89-92.
Taga ME, Larsen NA, Howard-Jones AR, Walsh CT, Walker GC. 2007. BluB cannibalizes flavin to form the lower ligand of vitamin B12. Nature. 446(7134):449-53.
Jones KM, Kobayashi H, Davies BW, Taga ME, Walker GC. 2007. How rhizobial symbionts invade plants: the Sinorhizobium-Medicago model. Nature reviews. Microbiology. 5(8):619-33.
2006
Campbell GRO, Taga ME, Mistry K, Lloret J, Anderson PJ, Roth JR, Walker GC. 2006. Sinorhizobium meliloti bluB is necessary for production of 5,6-dimethylbenzimidazole, the lower ligand of B12. Proceedings of the National Academy of Sciences of the United States of America. 103(12):4634-9.
2005
Taga ME. 2005. Methods for analysis of bacterial autoinducer-2 production. Current protocols in microbiology. Chapter 1:Unit1C.1.
2004
Miller ST, Xavier KB, Campagna SR, Taga ME, Semmelhack MF, Bassler BL, Hughson FM. 2004. Salmonella typhimurium recognizes a chemically distinct form of the bacterial quorum-sensing signal AI-2. Molecular cell. 15(5):677-87.
2003
Taga ME, Bassler BL. 2003. Chemical communication among bacteria. Proceedings of the National Academy of Sciences of the United States of America. 100 Suppl 2:14549-54.Taga ME, Miller ST, Bassler BL. 2003. Lsr-mediated transport and processing of AI-2 in Salmonella typhimurium. Molecular microbiology. 50(4):1411-27.
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